Hyaluronic Acid & Your Favorite Skincare Ingredients: How They Work Together

Hyaluronic acid is one (if not the one) of the most popular skincare ingredients. It is not a surprise that many women who have tried it continue to use it. This ingredient binds 1000 times its weight in water. The skin is soothed, well moisturized, and glowy when you use hyaluronic acid products. 

However, have you ever wondered how hyaluronic acid works with other skincare ingredients, like niacinamide, vitamin C, and others? Read on to learn how you can combine all these active ingredients and what to expect on your skin after incorporating them. 


Niacinamide is also known as vitamin B derivate. You have probably heard it under the name vitamin B3, and it is water-soluble. It is very effective in clearing acne, fading discoloration, minimizing the pores on your face, as well as reducing fine lines and wrinkles. Another great thing about this ingredient is its compatibility with other skincare ingredients. 

How Do They Work Together?

Hyaluronic acid and niacinamide work perfectly together. These water-based ingredients hydrate the skin, leaving your skin glowy and all fine wrinkles minimized. All you need to do is to find a moisturizer that combines these two. 

Salicylic Acid

Salicylic acid is a beta-hydroxy acid. It can be found as a natural compound in plants. BHAs are more oil-soluble, meaning they can penetrate deeper into the skin, at a deeper level than water-soluble products. Since salicylic acid promotes exfoliation, it also has antibacterial properties and anti-inflammatory agents. A perfect ingredient for acne, found in face washes and acne treatments. 

How Do They Work Together?

Mixing these two ingredients is common. Since salicylic acid can leave your skin a bit dry, hyaluronic acid will provide more moisture and lock it in. 

Glycolic Acid

Glycolic acid is an AHA (alpha-hydroxy acid) and it is derived from sugarcane. This type of acid has anti-inflammatory effects and it is water-soluble. Glycolic acid is made of tiny molecules that make your skin accept them easily, so they can penetrate well. This property makes glycolic acid perfect for improving fine lines and wrinkles, as well as skin texture. 

How Do They Work Together?

Glycolic acid works as an exfoliator, while hyaluronic acid works as a hydrator. One of the main benefits glycolic acid can bring is skin cell turnover, but that can lead to skin irritation. So, putting on hyaluronic acid afterward can be soothing giving you dewy skin since moisture will be locked in. 

Lactic Acid

Lactic acid is another exfoliant derived from the fermentation of lactose. It is an alpha-hydroxy acid, a chemical exfoliant that improves the skin texture and hydrates it very well. It is also popular due to its properties to increase cell turnover, eliminate dead skin cells, and lead to a brighter and smoother complexion. 

How Do They Work Together?

Hyaluronic acid and lactic acid work perfectly together, just like glycolic acid. While lactic acid exfoliates the skin, hyaluronic acid hydrates it. Lactic acid starts by removing dead skin cells. Hyaluronic acid is nourishing so your skin is soft, smooth, and hydrated in the end. 


Squalane comes from squalene, which can be found in plants, people, and animals. Squalane is a natural lipid that protects and moisture your skin. Both squalene and squalane are great in providing moisture and improving elasticity in the skin. This ingredient is great for scar treatment, hyperpigmentation, and sun damage. 

How Do They Work Together?

Squalane and hyaluronic acid are naturally found in the human body. Moreover, they work perfectly together to fight against signs of aging and to keep the moisture barrier at the highest level possible. Furthermore, these two are a powerful duo that locks the moisture, keeps skin’s water level high, and optimal skin health. 

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Thick As Thieves Pure Glycolic Acid Lactic Acid Extreme Gel Peel